One of the longest-running scripted television programs in the world, it premiered on November 8, 1965.

The show was created around the marriage, children, and family of Dr. Tom Horton (Macdonald Carey) and his wife Alice (Frances Reid).

Bo Brady and Hope Williams changed the face of daytime when rebel Bo came riding into town on his motorcycle in 1983 and fell for the rich and feisty Hope Williams, whom he later nicknamed Fancy Face.

In 2003, a masked serial killer murdered a huge chunk of the show's most beloved characters. Who would do such a thing? Turned out it was a brainwashed Marlena Evans killing off her friends and neighbors!

The January 12, 1976 cover of Time magazine featured Days of Our Lives actors Bill Hayes and Susan Seaforth Hayes, the only daytime actors ever to appear on its cover. The real-life couple met in 1970 while portraying Doug and Julie Williams on Days of Our Lives.

Bo and Hope rode off together on Bo's motorcycle, while Bo's friend Howie stood in for the bride.

Stefano's most iconic possession is a gold ring with a black flat square on top. It is embroidered with a Phoenix and is said to be the reason why Stefano keeps coming back to life.

In 1995, Marlena was featured in a supernatural possession storyline. Soap Opera Digest editor Stephanie Sloane said the story "completely changed the face of daytime storytelling in the 1990s," but Entertainment Weekly called it "The Dumbest Soap Plot Ever."

When Bo faced a health crisis in March 2008, daughter Chelsea saved his life by donating part of her pancreas.

Along with General Hospital's Luke and Laura Spencer, Bo and Hope are considered to be one of daytime's most iconic couples. The couple is often referred by the portmanteau "Bope" (for Bo and Hope).