Stewie confides all his secrets and machinations to Rupert and often gets upset when Rupert does not respond. Rupert has also been known to double as a pistol when needed.

Brian, the Griffins' talking white Labrador, went to Brown University in Rhode Island, but did not graduate. He is also a member of MENSA.

Peter is particularly proud of the fact that she once slept with Gene Simmons of Kiss but forbids any sexual activity between the two now as seen in "Don't Make Me Over".

Patrick Pewterschmidt became a serial killer known as the Quahog Fat Guy Strangler, strangling fat guys to death. He nearly killed his own brother-in-law Peter Griffin.

Brian was fired once the magazine learned he did not graduate from college.

In "Stewie Griffin: The Untold Story", Brian is seen in Heaven at a table drinking martinis with Vincent van Gogh, Kurt Cobain, and Ernest Hemingway. All three claim to have killed themselves out of some passion. Brian then admits that he ate some bad chocolate out of the trash can.

in "Stew-Roids", it is shown that Meg gets food waste for school lunch i.e. peels, crusts and a taunting picture of Lois eating a turkey leg.

In "The Story on Page One", he spent $100,000 of taxpayer money to investigate who was "stealing his water" and agreed to have sex with Luke Perry so he would stop stealing his water, when in fact it was going down the drain just as it was supposed to.

The four friends entered and won a costume contest at an 80s TV convention in "Brian Goes Back to College", dressing up as the A-Team.

In "Blind Ambition", Crackle and Pop survive an attack by the Keebler Elves. Snap isn't so lucky.