Talbot is a close compatriot to General Thaddeus Ross and an active participant in his operations to capture or kill the Hulk. It is Talbot who discovers and informs his superiors that Banner is the Hulk, which of course makes him a wanted fugitive.

Emil Blonsky first appeared in Tales to Astonish #90 and was introduced as a KGB agent and spy who became the Abomination after deliberately exposing himself to a greater quantity of the same gamma radiation that transformed Bruce Banner into the Hulk. When writer Stan Lee first introduced the character to artist Gil Kane, he said, "just make him bigger and stronger than the Hulk and we'll have a lot of fun with him."

Samuel Sterns was a janitor working in a chemical plant until exposure to gamma radiation transformed him into a green-skinned, super-intelligent entity with an oversized brain housed in a towering cranium. Calling himself the Leader, Sterns embarks on various ambitious criminal schemes, with the Hulk as his primary nemesis, consistently backed by a self-constructed army of super-strong, virtually invulnerable plastic Humanoids.

Jarella is the princess of the sub-atomic kingdom of K'ai. She accepts Hulk unconditionally, coming to love both sides of his dual personality, and they seem fated to live happily ever after until the supervillain Psyklop snatches Hulk unexpectedly from the Microverse.

Approximately a hundred years into the future, a nuclear war has killed almost all of Earth's superhumans and has taken the world to the brink of extinction. A future version of the Hulk called the Maestro has seized control after being driven insane by the nuclear radiation he has absorbed and the bitterness he feels towards the world for refusing to accept him.

Grey Hulk finds a way to repress the Bruce persona for months at a time. He takes the name Joe Fixit and sets himself up as a morally ambiguous enforcer working for a mobster in Las Vegas. The Bruce persona eventually resurfaces, and the two begin leaving threatening messages for each other.

The Hulk was a founding member of the Avengers, though he didn't last long. And while the lineup of the Defenders has often rotated, the three core members have always been Doctor Strange, Namor, and the Hulk. But those aren't his only affiliations. When a Skrull alien captured the original Fantastic Four and made it seem as if the team had died, a new group banded together to avenge the missing heroes. The team included Wolverine, Ghost Rider, Spider-Man and the gray-skinned Hulk.

Hulk has proven to be able to see ghosts as well as people on the Astral Plane. This was first examined in the pages of The Defenders when Doctor Strange insulted Hulk's intelligence from the Astral Plane ... and Hulk responded. A more disturbing example came later when Hulk saw the ghost of his deceased abusive father, something that began to drive him insane.

After being exiled from Earth by the Illuminati, Hulk finds himself on the planet Sakaar, where he is imprisoned and forced into gladiatorial combat. Hulk unites with other gladiators to form the group known as the Warbound and leads a series of battles against the Red King and his imperials, eventually overthrowing him.

Skaar is the son of Hulk and Caiera the Oldstrong, who conceived Skaar during the Hulk's time on Caiera's home planet, Sakaar.