Houseflies have chemoreceptors, organs of taste, on the tarsi of their legs, so they can identify foods such as sugars by walking over them. Houseflies are often seen cleaning their legs by rubbing them together, enabling the chemoreceptors to taste afresh whatever they walk on next.
Male houseflies are sexually mature after 16 hours and females after 24. The life cycle can be completed in seven to 10 days under optimal conditions, but may take up to two months in adverse circumstances.
House flies are synanthropic organisms, meaning they benefit ecologically from their association with humans and our domesticated animals. As humans throughout history traveled to new lands by ship, plane, train, or horse-drawn wagon, house flies were their travel companions. Conversely, house flies are rarely found in the wilderness or in places where humans are absent. Should humankind cease to exist, house flies might share our fate.
Houseflies serve as mechanical vectors to over 100 pathogens, such as those causing typhoid, cholera, salmonellosis, bacillary dysentery, tuberculosis, anthrax, ophthalmia, and pyogenic cocci, making them especially problematic in hospitals and during outbreaks of certain diseases.
During the Second World War, the Japanese worked on entomological warfare techniques under Shirō Ishii. Japanese Yagi bombs developed at Pingfan consisted of two compartments, one with houseflies and another with a bacterial slurry that coated the houseflies prior to release. Vibrio cholerae, which causes cholera, was the bacterium of choice, and was used in Baoshan, China in 1942 to produce an epidemic that ultimately claimed 200,000 victims.
Houseflies have many predators, including birds, reptiles, amphibians, various insects, and spiders.
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