Doug Hamilton won the Major League Soccer Executive of the Year award three straight times, from 2003 to 2005, but the 43-year-old general manager suffered a fatal heart attack on March 16, 2006, on board a plane carrying the team back from Costa Rica where they had played Saprissa in the CONCACAF Champions' Cup. After his passing, the MLS Executive of the Year award was renamed the Doug Hamilton Executive of the Year Award.

The Galaxy's chief rivalry match is played against the San Jose Earthquakes, which is known by the fans and media as the California Clásico. It is considered among the fiercest and longest-running rivalries in American soccer.

Landon Donovan's three goals in the 2010 World Cup made him the highest-scoring male American player in World Cup history and one of just three male American players to score in more than one World Cup, along with Brian McBride and Clint Dempsey.

Beckham wore the No. 7 shirt during most of his career at Manchester United and with England, before switching to No. 23 (the number worn by basketball legend Michael Jordan) during his time with Real Madrid and L.A. Galaxy.

Eduardo Hurtado was one of the early stars of Major League Soccer, scoring the second most goals in the league's opening season and helping the Los Angeles Galaxy make a run for the playoffs.

With 164 caps, Cobi Jones is currently the all-time leader of the United States in appearances. He played for the team in the 1994, 1998, and 2002 FIFA World Cups. He was named to the best XI at the 2000 CONCACAF Gold Cup and won with the national team at the 2002 CONCACAF Gold Cup. He also represented his country at the 1992 Summer Olympics in Barcelona.

Robbie Keane scored 68 goals for the Republic of Ireland national team over an 18-year international career, making him the all-time record Irish scorer. His 146 caps is also an Irish record.

In March 2007, Herbalife became the club's primary shirt sponsor, signing a deal worth between $4-5 million a year.

On January 15, 2015, MLS renamed its MVP award in honor of Landon Donovan, who won a record six MLS Cups and is the league's all-time assists leader with 136.

The Galaxy played the New England Revolution in the 2014 MLS Cup and won 2-1 in overtime, becoming five-time champions, a league first.