Misha is the co-founder and board president of Random Acts of Kindness, a non-profit organization aiming to conquer the world one random act of kindness at a time.

On April 1st 2013, users of Tumblr changed their icons to a picture of Misha. It has since become known as the Mishapocalypse -- the day tumblr users unite as one -- one Misha.

In the second season of Charmed, Misha plays Eric Bragg, a mortal who uncovers the location of the Akashic Records, which foretells all significant events throughout time. He is hunted by two warlocks called the Collectors, who want to extract his knowledge to obtain the records for themselves.

Misha spent time at a monastery in Nepal. He still practices Buddhist meditation and goes on a 10 day retreat once a year.

In 2011, Misha founded the Greatest International Scavenger Hunt the World Has Ever Seen, an annual week-long competition that holds the record for world's largest media scavenger hunt. As part of the competition, Misha also set world records for largest online photo album of hugs and longest chain of safety pins.

Misha and Supernatural co-star Jared Padalecki both use sign language with their children.

On October 6, 2001, Collins married Victoria Vantoch, his high school sweetheart.

During high school, Misha's house burned down.

Misha refers to his Twitter followers as "minions" and has repeatedly claimed that he has plans for world domination (through random acts of kindness).

Before becoming an actor, Misha worked for six months as a White House intern for Bill Clinton. He was placed in The Office of Presidential Personnel.