Sylvester J. Pussycat, Sr. first appeared with Tweety in the 1947 short "Tweetie Pie" in which he initiates a series of failed attempts to get the bird from his cage, each ending in a noisy crash bringing the lady of the house to whack Sylvester with a broom, and then finally, throw him out.
Granny is usually depicted as the owner of Tweety (and more often than not, Sylvester the Cat and Hector the Dog as well).
In his very first appearance in A Tale of Two Kitties (1942), Tweety uttered what would become his signature line: "I tawt I taw a puddy tat!" usually followed by "I did! I did taw a puddy tat!"
In The Sylvester and Tweety Mysteries (1995-2002), Granny runs a detective agency with the assistance of Tweety, Sylvester and Hector. In the final episode of the series, Sylvester finally succeeds in eating Tweety after decades of trying, but it turns out to be a dream.
In Hyde and Go Tweet (1960), Sylvester chases Tweety into Dr. Jekyll's lab, where he is accidentally transformed into a crazy evil laughing giant bird-monster that begins chasing Sylvester.
In A Tale of Two Kitties, Tweety is being stalked by Babbit and Catstello, two cats based on the popular comedy duo Abbott and Costello.
Many of Mel Blanc's characters are known for speech impediments. One of Tweety's most noticeable quirks is that /s/ is changed to /t/, so that "pussy cat" becomes "putty tat" and "sweetie pie" becomes "tweetie pie".
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